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Dr. Alice A. Ruram
Professor & HOD
MD Biochemistry
Reg. No.: 15036 - Assam medical Council |
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Dr Happy Chutia
Additional Professor
MD Biochemistry
Reg. No.: 17615 - Assam Medical Council |
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Dr Polina Boruah
Asst. Professor
MD Biochemistry
Reg. No.: 16119 - Assam Medical Council |
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Senior Resident Doctor:
- Dr. Racheal S. Marbaniang
- Dr. Mitali Roy
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The Department of Biochemistry is an academic basic science department, actively engaged in teaching, diagnostic support, training and research. Undergraduate courses taught include MBBS and BSc nursing. At present on an average more than 400 patients samples are processed in the biochemistry laboratory per day for various clinical investigations. Around 1500 to 2000 numbers of various biochemical investigations are performed per day. Since January 2008 the Clinical Biochemistry Laboratory is operating 24hrs/day providing uninterrupted and unremitting emergency service to the patients visiting NEIGRIHMS. |
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Infrastructure |
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Department of Biochemistry is well equipped with most of the high-quality Clinical Biochemistry Laboratory equipments:
- Fully Automated Clinical chemistry analyzer ( Beckman Coulter, AU2700 plus)-1
- Fully Automated Clinical chemistry analyzer ( Beckman Coulter, AU480)-1
- Fully Automated Dry chemistry Clinical analyzer ( Johnson’s and Johnson’s, vitros 4600)
- Fully Automated Clinical chemistry analyzers (Transasia Erba XL-600 and Erba 300)-1 each
- Fully automated Chemiluminescence system (Beckman Coulter, Access 2)– 1
- Fully automated Chemiluminescence system (Beckman Coulter, DXI 800) - 1
- Fully automated Nephelometer system (Beckman Coulter, Immage )- 1
- Fully automated ELISA processor system (Transasia, Mago-4 )- 1
- Semiautomatic clinical chemistry analyzers (Make- Erba, Model no- Chem 5X) -2
- Electrolyte analyzers from Eschweiler combiline -4
- Electrolyte analyzer (Erba Easylyte)-1
- Automated Electrolyte analyzers with sample tray (Caretium, BR Medical) -2
- Automated HbA1C analyzer (Biorad, Model No D 10)-1
- Clinical centrifuge-5
- Refrigerated centrifuge- 2
- Water purification system (Milipore Elix 3 and Mili Q)-1
- Water purification system (Milipore Elix-70)-1
- Water purification system (Thermofisher Maxi Tower plus )-1
- Fully automated electrophoresis system from Helena Bioscience with SAS-1 and SAS-2-1
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Basic Research Equipments available in the Department |
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- High speed refrigerated centrifuge (Eppendorf &Thermofisher Scientific )-3
- UV Spectrophotometer-1(MRC lab)
- Electrophoresis system with power pack-1 (Genetix)
- Gradient Thermal Cycler (Eppendorf)-1
- Laminar air flow (Nuaire)-1
- Deep Freezer (-20 and -80) from Dometic -1 each
- ELISA reader and washer (Biorad) -1
- Lyophilizer (Delvac Pumps)-1
- BOD Incubator(Acmas)-1
- HPLC system (Thermofischer scientific)-1
- Real Time PCR (Rotor Gene) from Qiagen
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Apart from routine tests, hormone assays, viz., thyroid, fertility, renal, tumor markers ,serum protein electrophoresis are done . In the year 2015 we started analysis of 25(OH) vitamin D, Antimullerian Hormone and D Dimer. Furthermore the Biochemistry Laboratory is also routinely conducting biochemical analysis of Urine and various other fluids such as cerebrospinal fluid, peritoneal fluid, pleural fluid etc.
The Clinical Biochemistry Laboratory is also actively involved in stringent Quality Control Programs. Third party Biorad and Randox Internal Quality Control as per the guidelines of ICMR and Quality Council of India are done on a regular basis to verify and validate the reports generated in the Clinical Biochemistry Laboratory. Moreover the Department is also participating in an External Quality Control program in association with EQAS of Association of Clinical Biochemists of India (ACBI) conducted by Christian Medical College, Vellore.
List of Biochemical Tests done in Clinical Biochemistry Lab, NEIGRIHMS: |
- Blood Sugar
- Glucose Tolerance Test
- Glycated Hemoglobin.
- Urinary Microalbumin
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Pancreatic Markers |
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Renal Function Tests and Electrolytes |
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- Cystatin C- started in 2013
- Uric Acid
- Sodium
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- Potassium
- Chloride
- Ionized Calcium
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Liver Function Tests |
- Bilirubin-Direct, Indirect, Total
- AST
- ALT
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Cardiac Markers |
Lipid Profile |
Minerals |
- CPK
- CKMB
- Troponin I
- LDH
- D Dimer
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- Cholesterol
- Triglyceride
- HDL
- LDL
- VLDL
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- Magnesium
- Phosphate
- Calcium
- Lithium
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Immunoassay |
- Free T3
- Free T4
- Total T3
- Total T4
- TSH
- Thyroglobulin
- Antibody to thyroglobulin
- LH
- FSH
- Prolactin
- Estradiol
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- Testosterone
- Progesterone
- Estriol
- DHEAS
- AFP
- CEA
- B HCG
- Ca-125
- Ca -19-9
- CA-15-3
- PTH
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- Insulin
- PSA
- Free PSA
- Cortisol
- Vitamin B12
- Folic acid
- 25(OH) vitamin D
- Antimullerian hormone
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Special Test |
- C3
- C4
- CRP
- Serum Protein electrophoresis
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The Department of Biochemistry also added another feather to its cap with the introduction MBBS academic program at NEIGRIHMS. The first batch of 50 students was admitted at NEIGRIHMS in September 2008. Since then the faculty and the resident doctors of the Department of Biochemistry have been actively involved in conducting both theory and practical classes to the MBBS students. Tutorials as well as Periodic Internal Assessments through Semesters were also given to asses the progress of the students. Besides the academic activities in the institution, the faculties are also involved in conducting 1st MBBS examinations, BDS examination in other medical colleges or institutions as external examiner
The Department has also proposed to start the M.D. Biochemistry courses . It is also actively involved in tutoring students enrolled in the institution via Theory and Practical classes for B.Sc. Nursing course including Periodic Internal Assessments through Semesters.
The Department also takes part in the different institutional and regional academic activities on a regular basis for the development of medical man power in the region as per the mandate of the institute. |
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Year |
Total number of patient samples analyzed |
Total number of tests done |
Jan 2008-December 2008 |
36,322 |
2,42,106 |
Jan 2009- December 2009 |
46,028 |
3,26,977 |
Jan 2010- December 2010 |
51,188 |
3,10,895 |
Jan 2011-December 2011 |
57,440 |
3,35,349 |
Jan 2012-December 2012 |
72,895 |
4,36,885 |
Jan2013-December 2013 |
88621 |
639769 |
Jan 2014- December 2014 |
99517 |
653144 |
Jan 2015-December 2015 |
1,26,206 |
8,13,386 |
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Research Projects in the Department- Completed |
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- Study of iodine deficiency disorders and abnormal thyroid function test in pregnant women and their neonates in NEIGRIHMS- funded by ICMR
- Childhood obesity in India : A multicentric study on measurements and determinants funded by ICMR
- Study of Thyroid profile status of MDR TB patients under DOTS Plus treatment in East Khasi Hills district of Meghalaya
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Research Projects in the Department-Ongoing |
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- Study of glucose 6 phosphate Dehydrogenase deficiency &G6PD gene polymorphism with reference to G6PD B & G6PD (A+/A_)genotype in patient treated for malaria in NEIGRIHMS –funded by DBT
- Early detection of kidney injury due to broad spectrum antibiotics use in critically ill patients with reference to cystatin C & neutrophil gelatinase associated lipocalin funded by DBT
- Prevalence of Vitamin D Deficiency and Insufficiency among the health care Professionals working in NEIGRIHMS, Shillong
- Study of serum Vitamin D status in pregnant women and its association with maternal complication-A hospital based study
- CA-125 in the diagnosis of operationally defined pulmonary tuberculosis
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Vision of the Department |
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The Department has vision in starting the molecular diagnosis facility in near future which is an urgent need in the region of NE India. In this respect procuring one automated microarray system is in process. Once equipped with real time PCR, Capillary electrophoresis (32 channels), Microarray system, FISH the department will start the molecular diagnosis on regular basis.
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